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Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
Listeria monocytogenes is a bacterial pathogen that can cause systemic infections in humans and animals. During infection these Gram-positive bacteria grow preferentially within the cytosol of a variety of cells of the infected organism. The listerial virulence genes essential for cell invasion, intracellular survival and replication and the differential regulation of these genes during the infection process have been extensively studied. Much less is known, however, of how these intracellular bacteria adapt to the metabolism of the host cells. In this presentation recent studies are discussed which show that the intracellular L. monocytogenes employs characteristic metabolic reactions. It is further shown that the expression of the virulence genes necessary for carrying out the intracellular growth cycle is closely linked with this intracellular metabolism. The identification of the specific intracellular metabolic reactions offer interesting targets for the inhibition of intracellular listerial growth thus blocking a L. monocytogenes infection.
Information on participating / attending:
Date:
01/23/2008 18:00 - 01/23/2008 20:00
Event venue:
Alfried Krupp Wissenschaftskolleg Greifswald
Martin-Luther-Straße 14
17489 Greifswald
Mecklenburg-Vorpommern
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
regional
Subject areas:
Biology, Chemistry, Information technology, Medicine, Nutrition / healthcare / nursing
Types of events:
Entry:
01/18/2008
Sender/author:
Stefan Klatt
Department:
Alfried Krupp Wissenschaftskolleg Greifswald
Event is free:
yes
Language of the text:
German
URL of this event: http://idw-online.de/en/event22426
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