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09/06/2010 - 09/10/2010 | Greifswald

Protein Engineering - Rational Design & Directed Evolution

Participants will be introduced into the scientific background
and the state-of-the-art methods of protein engineering. The
focus will be on evolutive methods (directed molecular
evolution) and rational protein design. The topic will be
addressed by lectures providing the required molecular biology,
computational and chemistry background, detailed introduction
into various methodologies and case studies. This should
enable participants to solve future problems of their own
research projects.

Enzymes are ideally suited as biocatalysts for the
development of sustainable and environmentally friendly
processes. Due to their high chemo-, regio- and
stereoselectivity and their activity at low temperatures and
ambient pressures, enzymes are currently used in areas
such as pharmaceutical synthesis and fine chemistry.
However, not all enzymes are designed by nature for
efficient application and hence their properties need to be
optimized. Protein engineering is the key method to tailordesign
enzymes, but also to investigate their structurefunction
relationships in basic research.
Due to the rapid development of the tools available for
protein engineering in the past decade, researchers have
the problem of too many choices when trying to engineer a
given enzyme.
This course aims to provide a state-of-the-art overview
about the various methods to allow an efficient and fast
protein engineering. This should enable the participants to
solve their future research problems more easily. The
summer school will cover all modern methods ranging from
rational protein design via focused directed evolution to
pure random mutagenesis in combination with screening or
selection. All methodologies will be presented and
discussed in detail by international speakers active in the
field.
The practicability will be taught in parallel experiments to
ensure that tips and tricks from experienced staff can be
applied "hands-on" by the participants.

Information on participating / attending:
Target Group
Scientists with background in Biology, Biotechnology,
Chemistry or related disciplines at the M.Sc., Ph.D. or Postdoc
level.

Registration
http://kwi.dechema.de/Weiterbildungskurse/alle+Kurstermine/Protein+Engineering+_...

Registration fee
390,- €
The course fee includes detailed course material, consumables
for laboratory experiments and coffee breaks.

Accommodation
A room contingent has been reserved at the Best Western
Hotel Greifswald (Phone: +49 3834 801-0, http://www.europagreifswald.
bestwestern.de) and at DJH Youth Hostel
Greifswald (Phone +49 3834 51690,
http://greifswald.jugendherbergen-mv.de
Please mention the code "UG-Direvo" for your reservation.

Adresse des Veranstaltungsortes:

Greifswald University
Institute of Biochemistry
Felix-Hausdorff-Str. 4
D-17487 Greifswald
Germany

Date:

09/06/2010 - 09/10/2010

Registration deadline:

08/09/2010

Event venue:

Greifswald University
Institute of Biochemistry
Felix-Hausdorff-Str. 4
17487 Greifswald
Mecklenburg-Vorpommern
Germany

Target group:

Scientists and scholars, Students

Email address:

Relevance:

international

Subject areas:

Biology, Chemistry, Economics / business administration, Medicine, Nutrition / healthcare / nursing

Types of events:

Entry:

06/15/2010

Sender/author:

Dr. Heinrich Cuypers

Department:

Presse- und Öffentlichkeitsarbeit

Event is free:

no

Language of the text:

German

URL of this event: http://idw-online.de/en/event31711


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