idw – Informationsdienst Wissenschaft
Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
During their lifetime, all types of cellular life face the constant threat of parasite genome invaders. In Bacteria and Archaea, CRISPR/Cas has recently emerged as an RNA-mediated adaptive immune mechanism against exogenous genetic elements. The system also known as the prokaryotic RNA interference (RNAi) pathway is composed of CRISPR-associated (Cas) proteins and short RNA molecules (CRISPR RNAs:crRNAs). The crRNAs consist of unique repeat/spacer sequences and commonly guide the Cas protein(s) to cognate invading nucleic acids for their destruction. A key event in CRISPR activation is the maturation of crRNAs.
We recently focused on one particular CRISPR/Cas system in the severe human pathogen Streptococcus pyogenes and discovered a unique crRNA biogenesis pathway together with a novel biological function of the immune pathway. A short overview of other lab projects regarding regulatory processes in Gram-positive bacterial pathogenicity will also be presented.
Who is Emmanuelle Charpentier?
•Faculty Positions: Assoc. Prof. MIMS, UCMR, Dep. of Molecular Biology, Umeå University, Sweden; Assoc. Prof. Max F. Perutz Laboratories, Univ. of Vienna, Austria; Assist. Prof. Dep. of Microbiology and Immunobiology, Univ. of Vienna, Austria; Guest Prof., Inst. of Microbiology and Genetics, Univ. of Vienna, Austria.
•Docent Degrees: Privat-Dozent, Habilitation in Microbiology, University of Vienna, Austria (2006); Docent, Faculty of Medicine, Umeå University, Sweden (2012).
Information on participating / attending:
Date:
02/16/2012 15:00 - 02/16/2012 17:00
Event venue:
TWINCORE, Zentrum für Experimentelle und Klinische Infektionsforschung
TWINCORE Lecture Hall
Feodor-Lynen-Str. 7
30625 Hannover
Niedersachsen
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
regional
Subject areas:
Biology, Chemistry, Medicine
Types of events:
Presentation / colloquium / lecture, Seminar / workshop / discussion
Entry:
01/18/2012
Sender/author:
Dr. Jo Schilling
Department:
Presse- und Öffentlichkeitsarbeit
Event is free:
yes
Language of the text:
English
URL of this event: http://idw-online.de/en/event38186
You can combine search terms with and, or and/or not, e.g. Philo not logy.
You can use brackets to separate combinations from each other, e.g. (Philo not logy) or (Psycho and logy).
Coherent groups of words will be located as complete phrases if you put them into quotation marks, e.g. “Federal Republic of Germany”.
You can also use the advanced search without entering search terms. It will then follow the criteria you have selected (e.g. country or subject area).
If you have not selected any criteria in a given category, the entire category will be searched (e.g. all subject areas or all countries).
