We will explain why most human phenotypes are under the influence of an enormous number of (mostly individually rare) genetic factors which vary both within and between populations. The failures of genome-wide association studies to identify important risk factors for common disease will be shown to be completely consistent with what evolutionary theory actually predicts and is likewise consistent with real data from genetic studies in agriculture and model organisms. Because a researcher cannot do genetic experiments in humans but is forced to work with observational data, we will further discuss how the researcher searches for and utilizes natural experiments that approximate the studies we would design if we had a more convenient species to study. Since evolutionary theory is so critical to understanding exposure distributions in genetic variation, it is critical for anyone working in genetic epidemiology to have a conceptual background in genetics.
Information on participating / attending:
Teilnahmegebühren: 700 Euro
Maximale Teilnehmerzahl: 30
Anmeldung online unter www.tmf-ev.de/school-extra
Date:
09/24/2012 11:00 - 09/28/2012 15:00
Event venue:
Veranstaltungsräume der TMF
Georgenstraße 22
10117 Berlin
Berlin
Germany
Target group:
Scientists and scholars
Email address:
Relevance:
international
Subject areas:
Medicine
Types of events:
Presentation / colloquium / lecture
Entry:
05/21/2012
Sender/author:
Antje Schütt
Department:
Geschäftsstelle TMF e.V.
Event is free:
no
Language of the text:
German
URL of this event: http://idw-online.de/en/event39784
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