idw – Informationsdienst Wissenschaft
Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
Abstract: DNA of higher organisms is highly compacted within the cell nucleus. DNA is wrapped around units of specialized proteins, forming cylindrical structures termed nucleosomes. This bead-on-a-string like structure called chromatin condenses further into chromosomes. While the structure of the DNA itself is known on an atomistic level, the higher level folding of chromatin remains enigmatic despite extensive research. We tackle this problem by using Monte Carlo-simulations applying Replica Exchange and Simulated Annealing procedures to integrate experimental knowledge from heterogeneous sources like single molecule experiments and high throughput sequencing. In this talk I will present our models, computational approaches and its applications in biophysics and systems biology.
Information on participating / attending:
Interessierte sind herzlich eingeladen!
Kaffee ab 16:30 Uhr vor dem GSR.
Organisation: Prof. H. Fehske und Prof. L. Schweikhard, Institut für Physik,
Felix-Hausdorff-Straße 6, 17489 Greifswald, Tel. 03834 86-4700, info@physik.uni-greifswald.de
Date:
06/20/2013 17:00 - 06/20/2013 18:00
Event venue:
Hörsaal Physik
Felix-Hausdorff-Straße 6
17489 Greifswald
Mecklenburg-Vorpommern
Germany
Target group:
Scientists and scholars, Students
Relevance:
regional
Subject areas:
Physics / astronomy
Types of events:
Presentation / colloquium / lecture
Entry:
05/29/2013
Sender/author:
Sabine Köditz
Department:
Presse- und Informationsstelle
Event is free:
yes
Language of the text:
German
URL of this event: http://idw-online.de/en/event43826
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