Abstract: Aptamers are oligonucleotides (DNA or RNA) which are capable of binding target molecules of any size and composition. They function like antibodies, however, built from nucleotides instead of amino acids, and are selected in vitro in the laboratory.
We have selected and characterized different aptamers specifically binding the interleukin-6 receptor (IL-6R). These IL-6R aptamers do not interfere with the Il-6 signaling pathway but are internalized with the receptor and thus can serve as vehicles for the delivery of different cargo molecules like therapeutics into special target cells.
Information on participating / attending:
Einladende: Prof. Dr. Winfried Hinrichs und
PD Dr. Heike Kahlert, Vorsitzende des Ortsverbandes der GDCh
Kontakt: Institut für Biochemie der Universität Greifswald
Felix-Hausdorff-Straße 4, 17489 Greifswald
Telefon 03834 86-4356, winfried.hinrichs@uni-greifswald.de
Telefon 03834 86-4452, hkahlert@uni-greifswald.de
Date:
07/03/2014 17:15 - 07/03/2014 18:15
Event venue:
Institut für Biochemie, Großer Hörsaal
Felix-Hausdorff-Straße 4
17489 Greifswald
Mecklenburg-Vorpommern
Germany
Target group:
Scientists and scholars, Students
Relevance:
regional
Subject areas:
Chemistry
Types of events:
Presentation / colloquium / lecture
Entry:
06/06/2014
Sender/author:
Sabine Köditz
Department:
Presse- und Informationsstelle
Event is free:
no
Language of the text:
German
URL of this event: http://idw-online.de/en/event47532
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