Metals are of utmost importance for all living organisms, because they assist important cellular processes of life such as energy production, enzyme catalysis, and the maintenance of genome integrity. At elevated concentrations, however, metals can become detrimental for the cell because of their high reactivity that may lead to toxic reactions such as the formation of radicals or the inhibition of protein binding sites. Therefore, the uptake, storage, intracellular distribution and protein insertion of metals has to be tightly regulated. In recent years many of the intricate molecular mechanisms underlying these processes have been discovered. Numerous metal transporters, metal storage proteins, metallochaperones, and assembly factors support all these diverse processes. Only their intimate cooperation and crosstalk ensures proper metalloprotein homeostasis and creates a healthy cell.
Functional impairment of any of these complex pathways or of the participating proteins may lead to severe human diseases with hematological, neurological and metabolic phenotypes. For a comprehensive understanding of metal and metalloprotein function in both healthy and diseased cells, the Mosbach Colloquium 2015 on ‘Metals in Biology’ is centered at the interface of Biochemistry, Cell Biology and Biomedicine. Outstanding scientists from Germany, Europe and the US will meet to discuss the latest findings in this research field.
Major progress has recently been made in our understanding of cellular trafficking of metal ions, and the involvement of metal ions in cellular signal transduction, enzyme function, electron transfer and protein stabilization. Considerable knowledge was gained on the assembly of metal centers in proteins, the role of metals in post-translational processing of proteins and in interorganelle communications. All relevant topics will be the focus of the meeting, presented by the world leading experts in five sessions:
- Metals in energy metabolism
- Metalloproteomics: Intracellular trafficking and homeostasis
- Biogenesis of metalloproteins
- Metals in enzyme function
- Metals in disease: Neurodegeneration, inflammation, infection and hematology
The meeting will be concentrated on trace elements including iron, copper, manganese, zinc, molybdenum and selenium.
About GBM
The German Society for Biochemistry and Molecular Biology (Gesellschaft für Biochemie und Molekularbiologie, GBM e.V.) is the largest organization for life sciences in Germany. With its almost 5,300 members, it is committed to serving the interests of all those working and researching in the dynamic and promising disciplines of chemistry, medicine and biology – from professors to first-year students. Whether it is the German Research Foundation (Deutsche Forschungsgemeinschaft), journalists, the authorities, or professional associations in other disciplines: anyone needing to call on expertise in questions of biochemistry and molecular biological sciences turns first and foremost to the GBM. For further information visit http://www.gbm-online.de.
About the Mosbacher Kolloquium
The Mosbacher Kolloquium is the annual spring conference of the German Society for Biochemistry and Molecular Biology (GBM). Since 1950, the GBM organizes this international meeting each time on a current main topic in the field of biochemistry and molecular biology. Venue is the picturesque town of Mosbach/Baden where leading experts from all over the world come together for this conference.
For further information and the current program please visit the website http://www.mosbacher-kolloquium.org
Contact person for the conference:
Prof. Dr. Roland Lill
Institut für Zytobiologie
Philipps-Universität Marburg
Robert Koch Str. 6
35037 Marburg
Tel.: +49-6421-286 6483 (Sekr.)
Fax: +49-6421-286 6414
Email: lill@staff.uni-marburg.de
Contact person at GBM:
Gesellschaft für Biochemie und Molekularbiologie (GBM e.V.)
Mörfelder Landstr. 125
60598 Frankfurt/Main
Tel: +49 (0)69 660567-0
Fax: +49 (0)69 660567-22
http://www.gbm-online.de
Dr. Anke Lischeid
Managing Director
Tel.: +49 (0)69 660567-12
Fax: +49 (0)69 660567-22
Email: lischeid@gbm-online.de
Information on participating / attending:
For information on registration please visit the website http://www.mosbacher-kolloquium.org/index.php/registration.html
Deadline for early-bird registration is on January 31st, 2015
Date:
03/25/2015 17:00 - 03/28/2015 12:30
Event venue:
Alte Mälzerei
Alte Bergsteige 7
74821 Mosbach
Baden-Württemberg
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
international
Subject areas:
Biology, Chemistry, Medicine
Types of events:
Conference / symposium / (annual) conference
Entry:
12/09/2014
Sender/author:
Dr. Anke Lischeid
Department:
Pressestelle
Event is free:
no
Language of the text:
English
URL of this event: http://idw-online.de/en/event49448
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