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Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
Resistance to antibiotics is a severe problem in contemporary medicine. Many antibiotics inhibit protein biosynthesis by hampering the ribosome function. Structures of bacterial ribosomes in complex with these antibiotics illuminated common pathways of antibiotics inhibitory action, but not the species-specific diversity in infectious-diseases susceptibility.
Recent structural studies on ribosome from a multi-resistant pathogenic bacterium and careful comparisons to ribosomes from non-pathogenic bacteria revealed novel structural motifs, essential to protein biosynthesis but not located in the primary ribosomal active sites, hence no mechanism for modification leading to resistance of these sites is currently known. These led to the design of antibiotics with desired properties that can be optimized in terms of their chemical properties, toxicity and penetration, alongside species-specificity, thus preserving the microbiome, as well as in terms of bio degradability, thus reducing the ecological hazards caused by the spread of the current antibiotics’ metabolites.
Information on participating / attending:
Die Anzahl der Plätze ist begrenzt. Um eine Anmeldung wird gebeten.
Date:
06/12/2019 18:00 - 06/12/2019 20:00
Event venue:
Hörsaal im Kaiserin-Friedrich- Haus
Robert-Koch-Platz 7
10115 Berlin
Berlin
Germany
Target group:
all interested persons
Email address:
Relevance:
transregional, national
Subject areas:
Biology, Medicine
Types of events:
Presentation / colloquium / lecture
Entry:
01/26/2018
Sender/author:
Caroline Wichmann
Department:
Presse- und Öffentlichkeitsarbeit
Event is free:
yes
Language of the text:
English
URL of this event: http://idw-online.de/en/event59528
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