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09/18/2025 - 09/19/2025 | Frankfurt am Main

GBM Compact - Focus on Condensate Biology

The existence of membrane-less organelles, such as nucleoli, stress granules or Cajal bodies has been known for a long time, but it has remained unclear how such organelles are actually formed, maintained or regulated. This meeting will bring together scientists from different disciplines to discuss how novel functions and pathologies emerge from the process of phase separation in biological systems, and what molecular underpinnings facilitate and regulate this key process.

The GBM Compact conference will present impressive possibilities on how to study and manipulate biomolecular condensates and subcellular architecture, for example using modern imaging and biophysical techniques. These will allow researchers to study single molecules, nanoclusters or large assemblies and to understand their dynamics, material properties and functions in vitro and inside cells.

While the existence of membrane-less organelles, such as nucleoli, stress granules or Cajal bodies has been known for a long time, it has remained largely unclear how such organelles are actually formed, maintained and regulated. We now know that compartments can also be formed by the phase separation of proteins, RNA and DNA and combinations thereof.

To investigate the newly emerging role of phase separation in biology, we need to develop new tools and approaches, as well as combine cell biology and biophysics with biochemical reconstitution, theory and modelling.

This meeting will bring together scientists from different disciplines which will synergistically decipher how novel functions and pathologies emerge from the process of phase separation in biological systems, and what molecular underpinnings facilitate and regulate this key process.

The meeting will start on Thursday, September 18 with the Fritz Lipmann Keynote Lecture by Michael Rosen (Department of Biophysics at UT Southwestern Medical Center and an Investigator of the Howard Hughes Medical Institute).

Information on participating / attending:
More information can be found on the GBM website

Date:

09/18/2025 12:00 - 09/19/2025 15:00

Event venue:

University Hospital Frankfurt
Haus 22
Theodor-Stern-Kai 7
60598 Frankfurt am Main
60598 Frankfurt am Main
Hessen
Germany

Target group:

Scientists and scholars, Students

Email address:

Relevance:

transregional, national

Subject areas:

Biology, Chemistry

Types of events:

Conference / symposium / (annual) conference, Presentation / colloquium / lecture

Entry:

04/24/2025

Sender/author:

Prof. Dr. Katharina Hieke-Kubatzky

Department:

Pressestelle

Event is free:

no

Language of the text:

German

URL of this event: http://idw-online.de/en/event79166

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