The GBM Compact conference will present impressive possibilities on how to study and manipulate biomolecular condensates and subcellular architecture, for example using modern imaging and biophysical techniques. These will allow researchers to study single molecules, nanoclusters or large assemblies and to understand their dynamics, material properties and functions in vitro and inside cells.
While the existence of membrane-less organelles, such as nucleoli, stress granules or Cajal bodies has been known for a long time, it has remained largely unclear how such organelles are actually formed, maintained and regulated. We now know that compartments can also be formed by the phase separation of proteins, RNA and DNA and combinations thereof.
To investigate the newly emerging role of phase separation in biology, we need to develop new tools and approaches, as well as combine cell biology and biophysics with biochemical reconstitution, theory and modelling.
This meeting will bring together scientists from different disciplines which will synergistically decipher how novel functions and pathologies emerge from the process of phase separation in biological systems, and what molecular underpinnings facilitate and regulate this key process.
The meeting will start on Thursday, September 18 with the Fritz Lipmann Keynote Lecture by Michael Rosen (Department of Biophysics at UT Southwestern Medical Center and an Investigator of the Howard Hughes Medical Institute).
Information on participating / attending:
More information can be found on the GBM website
Date:
09/18/2025 12:00 - 09/19/2025 15:00
Event venue:
University Hospital Frankfurt
Haus 22
Theodor-Stern-Kai 7
60598 Frankfurt am Main
60598 Frankfurt am Main
Hessen
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
transregional, national
Subject areas:
Biology, Chemistry
Types of events:
Conference / symposium / (annual) conference, Presentation / colloquium / lecture
Entry:
04/24/2025
Sender/author:
Prof. Dr. Katharina Hieke-Kubatzky
Department:
Pressestelle
Event is free:
no
Language of the text:
German
URL of this event: http://idw-online.de/en/event79166
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