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Image for: Lichtblicke für die Therapie des humanen Usher-Syndroms


Fluoreszenzmikroskopische Analyse von Zellen mit einer Nonsens-Mutation im Usher-Syndrom-1C-Gen (USH1C/Harmonin). Nach Applikation des Designer-Aminoglykosids NB54 wird die USH1C-Mutation überlesen und die therapierten Zellen produzieren das gesunde Harmonin-Protein (grün).
Fluoreszenzmikroskopische Analyse von Zellen mit einer Nonsens-Mutation im Usher-Syndrom-1C-Gen (USH1C/Harmonin). Nach Applikation des Designer-Aminoglykosids NB54 wird die USH1C-Mutation überlesen und die therapierten Zellen produzieren das gesunde Harmonin-Protein (grün).

Quelle: K. Nagel-Wolfrum, Institut für Zoologie, JGU

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