Disease phenotypes arise from complex interactions of organisms with their environments. While we have a long history of associating genes and gene defects with a large array of diseases, a growing body of data suggests that many disease phenotypes arise from gene-gene interactions and the interactions of genes with their environments - including the genetic background in which those genes are expressed. With the sequencing of the human genome and the genomes of model organisms, and the development of high-throughput technologies, we have now for the first time the means to dissect complex phenotypes and develop novel diagnostic, prognostic, therapeutic, and preventive strategies. While the principles underlying high-throughput technologies (e.g. cDNA microarrays) are relatively simple, the challenges associated with examining thousands of date points, and of presenting those data in a usable form are substantial. Further, the true value of the data lies not in the results of any single study, but rather, in examining correlations across multiple study groups and organisms. Developing an accurate interpretation of the generated data requires genomic information management systems capable of effectively capturing the data as well as tools to make that data accessible to the clinician. In this talk current trends and future challenges associated with the generation, management, storage, and analysis of high-throughput data will be highlighted with special emphasis on mammalian models of complex diseases.
Information on participating / attending:
Date:
04/28/2004 16:00 - 04/28/2004 17:30
Event venue:
Oberer Eselsberg, Universität West, Hörsaal 45.2
89081 Ulm
Baden-Württemberg
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
local
Subject areas:
Electrical engineering, Energy
Types of events:
Entry:
02/19/2004
Sender/author:
Peter Pietschmann
Department:
Presse- und Öffentlichkeitsarbeit
Event is free:
unknown
Language of the text:
German
URL of this event: http://idw-online.de/en/event10587
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