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09/30/2007 - 10/02/2007 | Cologne

23rd Ernst Klenk Symposium in Molecular Medicine: Non-Coding RNA

We would like to invite you to the 23. Ernst Klenk Symposium in Molecular Medicine on "Non-Coding RNA" which will be held from 30 September to 02 October, 2007 at the Main Lecture Hall of the Medical Faculty of the University of Cologne.

We are very pleased to announce that Prof. Thomas Tuschl (Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, The Rockefeller University, New York) was substantially involved in the scientific coordination of the program. Prof. Tuschl will also present the Ernst Klenk Lecture entitled "Mechanisms of Small RNA Guided Gene Silencing in Mammals".

The list of speakers includes leading researchers in the field who will discuss the breakthroughs and challenges of Non-Coding RNA technology
(see program: http://www.zmmk.uni-koeln.de/content/seminare/symposium/klenk/klenk_2007/program...).

The topics include the mechanism of small RNA guided gene silencing in fungi, plants and protozoa, microRNAs, siRNA in the context of diseases as well as the biochemical mechanisms of RNA silencing.

The Symposium - organized by the Zentrum für Molekulare Medizin der Universität zu Köln (ZMMK) and the Ernst Klenk Foundation (Marburg) - is intended to provide a forum for discussion of state-of-the-art research for interested scientists and students from academia and industry.

programm:

Sunday - September 30, 2007


2.00 - 2.10 p.m. Welcome Address

Axel Freimuth - Rector, University of Cologne, Germany

Martin Krönke - Chairman, CMMC, University of Cologne

Hans-Dieter Klenk - Chairman, Ernst Klenk Foundation



Session I:

Mechanism of small RNA guided gene silencing in fungi, plants, and protists (trypanosome, slime mould)

Chair:

Witold Filipowicz, Basel - Switzerland
2.10 - 2.50 p.m. The RNAi Machinery in Dictyostelium

Wolfgang Nellen
University of Kassel - Germany

2.50 - 3.30 p.m. RNA Silencing in Neurospora Crassa

Giuseppe Macino
Università di Roma "La Sapienza", Rome - Italy

3.30 - 4.10 p.m. RNAi in Trypanosomes, Divergent Protozoa Causing Parasitic Diseases

Philippe Bastin
Pasteur Institute, Paris - France

4.10 - 4.30 p.m.

- C o f f e e B r e a k -

4.30 - 5.10 p.m. RNA Silencing Networks in Plants

David Baulcombe
The Sainsbury Laboratory, Norwich - Great Britain

5.10 - 5.50 p.m. Systemic RNAi and Intercellular RNA Transport and Delivery

Craig P. Hunter
Harvard University, Cambridge MA - USA



Monday - October 01, 2007



Session II:


Other non-coding RNAs

Chair:
Mikiko C. Siomi, Tokushima - Japan

9.00 - 9.40 a.m. ncRNAs: A Hidden Layer of Gene Regulation in Genomes of Model Organisms

Alexander Hüttenhofer
Innsbruck Medical University, Innsbruck - Austria

9.40 - 10.20 a.m. The Codes of "Non-Coding" RNA

Jürgen Brosius
University of Münster - Germany

10.20 - 10.40 a.m.
- C o f f e e B r e a k -

10.40 - 11.20 a.m. A Panoramic View of Small Non-Coding RNA Function in a Bacterial Pathogen

Jörg Vogel
Max Planck Institute for Infection Biology, Berlin - Germany

11.20 - 12.00 a.m. Computational Detection and Annotation of Non-Coding RNAs

Ivo L. Hofacker
University Vienna - Austria

12.00 - 2.00 p.m.

- L u n c h B r e a k -



Session III:


microRNAs, siRNAs and disease

Chair:
Elisa Izaurralde, Tübingen - Germany

2.00 - 2.40 p.m. Large-Scale RNA Interference Screens to Identify Cancer-Relevant Genes

René Bernards
The Netherlands Cancer Institute, Amsterdam - The Netherlands

2.40 - 3.20 p.m. Functional Genetic Approaches Identify Cancerous miRNAs

Reuven Agami
The Netherlands Cancer Institute, Amsterdam - The Netherlands

3.20 - 3.40 p.m.

- C o f f e e B r e a k -
3.40 - 4.20 p.m. Computational Analyses of miRNA Target Sites

Mihaela Zavolan
University of Basel - Switzerland

4.20 - 5.00 p.m. Strategies to Study miRNAs in vivo

Markus Stoffel
Swiss Federal Institute of Technology Zürich - Switzerland

5.00 - 6.00 p.m.

- C o f f e e B r e a k -

6.00 - 7.00 p.m.
Ernst Klenk Lecture

Mechanisms of Small RNA Guided Gene Silencing in Mammals

Thomas Tuschl
Rockefeller University, New York - USA



Tuesday - October 02, 2007



Session IV:



Biochemical mechanism of RNA silencing

Chair:

Guiseppe Macino, Rome - Italy
9.00 - 9.40 a.m. Mechanisms of miRNA-Mediated Gene Silencing

Elisa Izaurralde
Max Planck Institute for Developmental Biology, Tübingen - Germany

9.40 - 10.20 a.m. RNA Silencing in Drosophila Germlines

Mikiko C. Siomi
University of Tokushima - Japan

10.20 - 10.40 a.m.

- C o f f e e B r e a k -

10.40 - 11.20 a.m. Role of Dicer in miRNA/RNAi Pathways and Regulation of miRNA Repression in Mammalian Cells

Witold Filipowicz
Friedrich Miescher Institute for Biomedical Research, Basel - Switzerland

11.20 - 12.00 a.m. Mechanism of Translational Control by Drosophila miR2

Matthias W. Hentze
European Molecular Biology Laboratory, Heidelberg - Germany
12.00 - 12.40 p.m. To Allow or to Impair RNA Silencing?

Javier Martinez
Academy of Sciences, Vienna - Austria

12.40 - 1 p.m. Summary and Concluding Remarks

Thomas Tuschl
Rockefeller University, New York - USA

Information on participating / attending:
free of charge

Date:

09/30/2007 14:00 - 10/02/2007 13:00

Event venue:

Center for Molecular Medicine of the University of Cologne (CMMC)
Building 44b, Joseph-Stelzmann-Str. 52
50937 Cologne
Nordrhein-Westfalen
Germany

Target group:

Scientists and scholars

Relevance:

international

Subject areas:

Medicine, Nutrition / healthcare / nursing

Types of events:

Entry:

09/26/2007

Sender/author:

Sina Vogt

Department:

Presse- und Öffentlichkeitsarbeit

Event is free:

yes

Language of the text:

English

URL of this event: http://idw-online.de/en/event21485


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