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01/09/2013 - 01/09/2013 | Greifswald

Enzymdesign mittels erweitertem genetischen Code

Das Institut für Biochemie lädt gemeinsam mit dem Ortsverband der Gesellschaft Deutscher Chemiker zu einem Kolloquium der GDCh ein. Professor Dr. Nediljko Budisa (TU Berlin, Institute of Technology) spricht zum Thema "Enzymdesign mittels erweitertem genetischen Code".

Abstract: „We have recently designed lipase congeners by global substitutions of canonical amino acids (cAAs) with corresponding non-canonical counterparts (ncAAs) in residue-specific manner. Expectedly, we have found that different ncAAs carrying various chemical modifications (e.g. fluorination, methylation, hydroxylation, etc.) dramatically altered the activity of lipase from the thermophilic anaerobic bacterium Thermoanaerobacter thermohydrosulfuricus (TTL). Observed effects include significantly enhanced activity, markedly extended substrate tolerance, large changes in optimal temperature and pH values."

Information on participating / attending:
Einladender: Prof. Dr. Uwe Bornscheuer
PD Dr. Heike Kahlert, Vorsitzende des Ortsverbandes der GDCh

Weitere Informationen: Institut für Biochemie, Prof. Dr. Uwe Bornscheuer,
Felix-Hausdorff-Straße 4, 17487 Greifswald, Telefon 03834 86-4367, uwe.bornscheuer@uni-greifswald.de

Date:

01/09/2013 14:15 - 01/09/2013 15:15

Event venue:

Großer Hörsaal
Institut für Biochemie
Felix-Hausdorff-Straße 4
17489 Greifswald
Mecklenburg-Vorpommern
Germany

Target group:

Scientists and scholars, Students

Relevance:

regional

Subject areas:

Biology, Chemistry

Types of events:

Presentation / colloquium / lecture

Entry:

01/04/2013

Sender/author:

Sabine Köditz

Department:

Presse- und Informationsstelle

Event is free:

no

Language of the text:

German

URL of this event: http://idw-online.de/en/event42080


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