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10/26/2019 - 10/29/2019 | Berlin

EMBO Workshop: The impact of bacterial infections on human cancer

The discovery of the gastric bacterium Helicobacter pylori led to the recognition that a bacterial infection can play a causal role in cancer development. Since then other bacteria - cancer relationships have become evident, e.g. for Chlamydia, Salmonella and E. coli. This meeting will bring together experts from different fields to discuss progress in this emerging research area, which has major implications for public health.

Pathogenic bacteria, in conjunction with other microbes, constantly affect our mucosal surfaces causing epithelial damage, particularly under chronic infection conditions. The most serious potential outcome is cancer, and it is almost certainly no coincidence that epithelial carcinomas represent the most common malignancy. While the causality between tumor viruses and human cancers is firmly established owing to the presence of viral transforming genes in the resulting cancer cells, no such clear genetic link has been seen for bacterial infections. Yet, H. pylori, the major risk factor of gastric cancer, is a paradigm for numerous intriguing observations suggesting a much broader relationship between persistent bacterial infections, microbiota, inflammation, and human cancers. Likewise, researchers have identified novel epidemiological relationships, bacteria-driven cancer-related signaling routes and genotoxins, and are beginning to understand the consequences of DNA damage and altered DNA damage repair, disturbed tissue homeostasis, chromosomal genetic and epigenetic changes, and the roles of chronic inflammation and the immune environment as carcinogenic conditions. This first comprehensive meeting with outstanding cancer researchers, medical scientists, micro- and cell biologists, employing diverse pathogen-related cancer models, will be a milestone for elucidating this intriguing relationship from different perspectives.

Information on participating / attending:
Students/Postdocs: EUR 300
Academics: EUR 450
Industry: EUR 700
Registration includes lunch, dinner and coffee breaks

Registration via the conference website

Date:

10/26/2019 08:00 - 10/29/2019 13:00

Registration deadline:

09/30/2019

Event venue:

Harnack House
The Conference Venue of the Max Planck Society
Ihnestr. 16-20
14195 Berlin
Berlin
Germany

Target group:

Scientists and scholars, Students

Relevance:

international

Subject areas:

Biology, Medicine

Types of events:

Seminar / workshop / discussion

Entry:

09/05/2019

Sender/author:

Christian Denkhaus

Department:

Presse- und Öffentlichkeitsarbeit

Event is free:

no

Language of the text:

English

URL of this event: http://idw-online.de/en/event64561


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