idw - Informationsdienst
Wissenschaft
11/18/2004 - 11/18/2004 | Greifswald
Referent: Prof. H.M.R. Hoffmann, Universität Hannover
Abstract:
Quinine has been among the best known alkaloids for over 300 years, thanks to its antimalarial activity. In the last two decades, Cinchona alkaloids have emerged as powerful chiral auxiliaries, resulting in some well known landmark developments in asymmetric synthesis, but more recently these alkaloids themselves have been shown to undergo some remarkable transformations and skeletal shifts that are rapidly widening perspectives in the chemistry of Cinchona bases, embracing both basic and applied science. The alkaloids enter into a series of fundamental transformations that have given rise to the industrial manufacture of a host of new enantiopure materials showing promise for asymmetric syntheses and combinatorial chemistry. Stereochemical diversity, well developed conformational minima not encountered in conventional organic substrates, hydrophilic pockets and stereoelectronics contribute subtle mechanistic features and structural complexity.
Information on participating / attending:
Einladender: Prof. Dr. Peter Langer, Institut für Chemie und Biochemie,
Tel. 03834-864461
Date:
11/18/2004 17:00 - 11/18/2004
Event venue:
Großer Hörsaal, Institut für Chemie und Biochemie
Soldmannstraße 16
17489 Greifswald
Mecklenburg-Vorpommern
Germany
Target group:
Scientists and scholars, Students
Email address:
Relevance:
transregional, national
Subject areas:
Biology, Chemistry, Information technology
Types of events:
Entry:
10/29/2004
Sender/author:
Sabine Köditz
Department:
Hochschulkommunikation
Event is free:
unknown
Language of the text:
German
URL of this event: http://idw-online.de/en/event12412
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