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11/18/2004 - 11/18/2004 | Greifswald

Recent Advances in Cinchona Alkaloid Chemistry

Kolloquium der GDCh
(Das Institut für Chemie und Biochemie lädt gemeinsam mit dem Ortsverband der Gesellschaft Deutscher Chemiker ein.)

Referent: Prof. H.M.R. Hoffmann, Universität Hannover
Abstract:
Quinine has been among the best known alkaloids for over 300 years, thanks to its antimalarial activity. In the last two decades, Cinchona alkaloids have emerged as powerful chiral auxiliaries, resulting in some well known landmark developments in asymmetric synthesis, but more recently these alkaloids themselves have been shown to undergo some remarkable transformations and skeletal shifts that are rapidly widening perspectives in the chemistry of Cinchona bases, embracing both basic and applied science. The alkaloids enter into a series of fundamental transformations that have given rise to the industrial manufacture of a host of new enantiopure materials showing promise for asymmetric syntheses and combinatorial chemistry. Stereochemical diversity, well developed conformational minima not encountered in conventional organic substrates, hydrophilic pockets and stereoelectronics contribute subtle mechanistic features and structural complexity.

Information on participating / attending:
Einladender: Prof. Dr. Peter Langer, Institut für Chemie und Biochemie,
Tel. 03834-864461

Date:

11/18/2004 17:00 - 11/18/2004

Event venue:

Großer Hörsaal, Institut für Chemie und Biochemie
Soldmannstraße 16
17489 Greifswald
Mecklenburg-Vorpommern
Germany

Target group:

Scientists and scholars, Students

Relevance:

transregional, national

Subject areas:

Biology, Chemistry, Information technology

Types of events:

Entry:

10/29/2004

Sender/author:

Sabine Köditz

Department:

Hochschulkommunikation

Event is free:

unknown

Language of the text:

German

URL of this event: http://idw-online.de/en/event12412


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