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05/25/2011 - 05/25/2011 | Hannover

TWINCORE Seminar

Wissenschaftlicher Vortrag am TWINCORE, Zentrum für Experimentelle und Klinische Infektionsforschung
PD Dr. Volker Thiel vom Institute of Immunobiology des Kantonal Hospital St. Gallen, Schweiz spricht zum Thema: "Coronaviruses: importance, dynamics and specificities of type-I interferon responses to cytopathic RNA virus infection"

The correct functioning of host innate immune responses to viral infections is based on reliable pathogen detection and is essential in limiting pathogen replication and spread. The presence of viral RNA activates cellular RNA sensors and results in expression of cytokines and type I interferon (IFN-I). IFN-I in turn signals to express an array of genes that restrict viral growth. Using coronavirus models of infection we study the importance, dynamics and specificities of IFN-I responses to cytopathic RNA virus infection. We focus in particular on important target cells of virus infections, such as dendritic cells and macrophages, and on the major producers of IFN-I during the early phase of the infection, namely plasmacytoid dendritic cells.

Who is Volker Thiel?

•Senior research fellow (group leader) at the Institute of Immunobiology (former Research Department), Kantonal Hospital St. Gallen, Switzerland (2003 - present).
•Member of the Vetsuisse Faculty, University Zürich.
•Temporary Advisor at the WHO Consultation on Needs and Opportunities for SARS Vaccine Research and Development.
•Before: Senior research fellow (group leader) at the Institute of Virology, University of Würzburg, Germany.

Information on participating / attending:

Date:

05/25/2011 12:30 - 05/25/2011 14:30

Event venue:

TWINCORE, Zentrum für Experimentelle und Klinische Infektionsforschung
TWINCORE Lecture Hall
Feodor-Lynen-Str. 7
30625 Hannover
Niedersachsen
Germany

Target group:

Scientists and scholars, Students

Email address:

Relevance:

regional

Subject areas:

Biology, Medicine, Nutrition / healthcare / nursing

Types of events:

Presentation / colloquium / lecture, Seminar / workshop / discussion

Entry:

04/04/2011

Sender/author:

Dr. Jo Schilling

Department:

Presse- und Öffentlichkeitsarbeit

Event is free:

yes

Language of the text:

English

URL of this event: http://idw-online.de/en/event34802


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