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03/30/2017 - 03/30/2017 | Ulm

ULM LECTURES - Prof. Emmanuelle Charpentier

Direktorin am Max-Planck-Institut für Infektionsbiologie Berlin, Trägerin des Gottfried Wilhelm Leibniz-Preises 2016

CRISPR-Cas9: a game changer in gene editing and genome engineering

Mit den ULM LECTURES bietet die Universität eine einzigartige Veranstaltungsreihe:
Hochkarätige, weltweit bekannte Wissenschaftlerinnen und Wissenschaftler berichten über ihre Forschungsthemen, einige davon sind Nobel- oder Leibnispreisträger.

Für die Universität ist es eine besondere Freude, diese Spitzenforscher in Ulm begrüßen zu dürfen und auch ein Ausweis für die hohe internationale Reputation des Forschungsstandorts.
Den Besucherinnen und Besuchern bietet sich die einmalige Gelegenheit, die Faszination aktueller Forschung "live" im Stadthaus erleben und erfahren zu können.

Abstract:
The CRISPR-Cas9 system has recently emerged as a transformative technology in biological sciences, allowing rapid and efficient targeted genome editing, chromosomal marking and gene regulation in a large variety of cells and organisms. The system consists of Cas9, an enzyme that can be programmed with RNA guides to target site-specifically any DNA sequence of interest. The system is efficient, versatile and easily programmable.
CRISPR-Cas9 research has developed into one of the most dynamic and fastest-moving fields in life sciences and holds great promise for future biotechnical and biomedical applications. The CRISPR-Cas9 system is remarkably simple in its design, close to a plug-and-play method, which can therefore be easily leveraged for a large variety of different gene targeting. Application of the system has been extraordinarily broad, including among many others the generation of transgenic animals, genetic modification of various eukaryotic cell types, and genetic modification of plants and crops. Already, the CRISPR-Cas9 system is an integral and critical part of the toolbox for any researcher who intends to manipulate genetic information by means of targeted introduction or correction of mutations, replacement of genes, modification of DNA or modulation of transcription in any cell or organism – and the applications of this breakthrough technology are continuing to increase at a rapid pace.
I will discuss the original biological role of CRISPR-Cas9 as an adaptive immune system in bacteria, the mechanisms involved, the evolution of the natural system and the applications of CRISPR-Cas9 as a novel genome engineering technology.

Information on participating / attending:
Dieser Vortrag findet in englischer Sprache statt.

Date:

03/30/2017 16:00 - 03/30/2017 17:30

Event venue:

Stadthaus Ulm, Münsterplatz 50
89073 Ulm
Baden-Württemberg
Germany

Target group:

Journalists, all interested persons

Email address:

Relevance:

transregional, national

Subject areas:

Biology, Medicine

Types of events:

Presentation / colloquium / lecture

Entry:

02/28/2017

Sender/author:

Martina Fischer

Department:

Pressestelle

Event is free:

yes

Language of the text:

German

URL of this event: http://idw-online.de/en/event56905


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