Zwischen den Zellen der Dünndarm-Deckzellschicht (blau) schlängelt sich ein Lymphozyt (gelb) hindurch. Die Zwei-Photonen-Mikroskopie stellt diesen Bewegungsvorgang erstmals im lebenden Gewebe direkt dar. Aus einem 3D-Movie von 11 Minuten Länge wurden sieben Momentaufnahmen mit verschiedenen Positionen desselben, wandernden Lymphozyten überlagert. Durch quantitative Analyse dieser Daten soll u.a. ermittelt werden, wie engmaschig die immunologische Überwachung der Darmschleimhaut durch Lymphozyten ist.
Bild: Prof. Dr. Andreas Gebert
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