idw – Informationsdienst Wissenschaft
Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
Abb. 1: Leukämiezelle mit einem intakten und einem gebrochenen BRWD3-Gen (drei rote Fluoreszenzsignale). Die Nachbarregion auf demselben Chromosom ist vom Chromosomenbruch nicht betroffen (zwei grüne Signale). Experiment: Fluoreszenz-in situ-Hybridisierung (Isolierte, mit Fluoreszenzfarbstoffen markierte Chromosomenteile erkennen die ihnen entsprechenden Regionen auf ganzen Chromosomen in Zellkernen und binden an diese, so dass diese Regionen im Mikroskop sichtbar werden).
Quelle: Dr. Claudia Kalla und DKFZ
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