Die Abbildung zeigt die prinzipielle Vorgehensweise der Transplantationsexperimente: Aus Zebrafischen mit fluoreszenz-markierten Nieren (grün) werden Zellen entnommen und in das Nierengewebe eines nicht markierten Empfängers (gelb) transplantiert. Wenige Tage danach sind in den Nieren des Empfängers voll funktionsfähige, fluoreszierende Nephrone, die funktionellen Untereinheiten der Niere, zu finden. Mehrmals hintereinander geschaltete Transplantationen von Nierenzellen liefern das gleiche Resultat: die Bildung neuer, fluoreszenz-markierter Nephrone, wobei die gefundene Anzahl entsprechend kleiner wird.
Quelle: C. Englert/FLI
(707 KB, 1055 x 916 pixels)
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