Das an der Uni Würzburg entdeckte Spir-Protein bringt die Bildung von Aktinfasern (F-Aktin) in Gang. Es wurde in Säugerzellkulturen hergestellt, seine Lokalisation in der Zelle mit fluoreszierenden Antikörpern sichtbar gemacht (rote Farbe). Das Protein befindet sich in der Nähe des bohnenförmig erscheinenden Zellkerns am so genannten trans-Golgi-Netzwerk (weißer Pfeil). Parallel wurden auch die Aktinfasern angefärbt (blau).
Bild: Kerkhoff
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