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Image for: How bacteria change movement direction in response to oxygen: Molecular interactions unravelled


Conformational changes within HemAT: When oxygen binds to the sensor domain (for methodological reasons, the experiment was carried out with carbon monoxide, CO, instead of oxygen), the protein conformation in the vicinity of the sensor domain changes. Thus, helices B and G are displaced. This affects the neighbouring H-helix which is continuous with the signalling domain.
Conformational changes within HemAT: When oxygen binds to the sensor domain (for methodological reasons, the experiment was carried out with carbon monoxide, CO, instead of oxygen), the protein conformation in the vicinity of the sensor domain changes. Thus, helices B and G are displaced. This affects the neighbouring H-helix which is continuous with the signalling domain.

Illustration: Samir El-Mashtoly

(487 KB, 1158 x 1042 pixels)

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