idw – Informationsdienst Wissenschaft
Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
There are a few signaling pathways that are all vital for the development of the embryo into a healthy organism and for maintaining life functions in the adult. These pathways operate from the cell surface to the cell nucleus with its DNA. When disrupted through mutations, severe diseases can result, such as cancer (e.g., colon cancer), brain and heart disorders, as well as other diseases. One of the best studied pathways today is the Wnt signaling pathway. It plays a crucial role in embryonic development, cell growth (proliferation), and maturation of cells into specialized cells (differentiation). This pathway is also an important regulator of stem cells. Two of the main compenents of the Wnt pathway are the proteins beta-catenin and TCF/LEF. In normal cells, the level of beta-catenin in the cytoplasm is regulated by a complex of proteins to which it is bound and which label it for destruction in the waste basket of the cell, the proteasome. One of them is the tumor suppressor APC (a
(Graphics: Jörg Hülsken/Copyright: MDC)
(70 KB, 600 x 450 pixels)
In regard to the use of pictorial material: use of such material in this press release is remuneration-free, provided the source is named. The material may be used only in connection with the contents of this press release. For pictures of higher resolution or inquiries for any further use, please contact the Press office publishing this directly.
Wir are looking for a
science communicator for the idw e.V.
You find all relevant [...]
Informationsdienst Wissenschaft has a new managing director: Dr. Svenja Niescken. Full details are [...]
You can combine search terms with and, or and/or not, e.g. Philo not logy.
You can use brackets to separate combinations from each other, e.g. (Philo not logy) or (Psycho and logy).
Coherent groups of words will be located as complete phrases if you put them into quotation marks, e.g. “Federal Republic of Germany”.
You can also use the advanced search without entering search terms. It will then follow the criteria you have selected (e.g. country or subject area).
If you have not selected any criteria in a given category, the entire category will be searched (e.g. all subject areas or all countries).
