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10/25/2019 15:09

4.5 Million Euros for Fundamental Research: Better Understanding of Cancer / Novel Materials in 2D

Kim-Astrid Magister Pressestelle
Technische Universität Dresden

    The European Research Council (ERC) is funding three research projects by young scientists at TU Dresden amounting to 4.5 million euros. From 2020, Prof. Julia Hauer, Dr. Mohamed Elgendy and Dr. Renhao Dong will each receive ERC Starting Grants of almost 1.5 million euros over a period of five years. Within the EU Framework Programme for Research and Innovation “Horizon 2020”, these grants are awarded to excellent scientists for innovative projects with a focus on fundamental research.

    Dr. Mohamed Elgendy: Understanding the Metabolism of Cancer Cells
    Rapid growth of tumour tissue and metastasis formation are major problems of cancers. Cancer cells use a higher amount of energy than normal body cells and therefore undergo a metabolic reprogramming. Cells usually use oxygen respiration for energy generation, while cancerous cells ferment glucose even in the presence of oxygen. This was first observed by Warburg in 1924 and is since known as the “Warburg hypothesis”.
    More recent work however highlights that cancer cell metabolism is more heterogeneous than anticipated. Dr. Mohamed Elgendy investigates the underlying molecular mechanisms of cancer metabolism. He also is interested to elucidate how cancer cell metabolism changes during chemotherapy and if this is possibly contributing to drug resistances.
    Project: ONco-Energetics_OFF – Dissection of Bioenergetic Plasticity of Tumors.
    Partners: Faculty of Medicine: Medizinische Klinik und Poliklinik I, Institut für Klinische Chemie und Laboratoriumsmedizin, Mildred Scheel Early Career Center
    Expected start: 1.3.2020
    Information and contact details: https://tu-dresden.de/med/mf/msnz/kollegiaten/mohamed-elgendy

    Prof. Julia Hauer: Tracing the Development of Childhood Leukaemia
    Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer and it remains a major cause of death in children aged 2-6 years in high-income countries. Genetic predisposition and exposure to infection, as a potential trigger for the development of childhood ALL was theorized a century ago with several possibilities of exposure to infection in infancy. Consequently, the overall objectives of PreventALL is to systematically analyze postnatally the genetic risk to develop ALL and to decipher the infectious mechanism by which exposure to infection causes ALL. This opens a new horizon for the understanding of leukemia etiology and foster innovation in the development of novel preventive strategies such as diet supplementation or vaccination.
    Project: PreventALL – Prevention of childhood Acute Lymphoblastic Leukemia immunology links oncology.
    Partners: Faculty of Medicine, Department for Pediatric Oncology and Haematology
    Expected start: 1.2.2020
    Information and contact details: https://www.uniklinikum-dresden.de/de/das-klinikum/kliniken-polikliniken-institu...

    Dr. Renhao Dong: 2D Materials for Novel Electronic Components
    Why think three-dimensionally when it works better with 2D? In his research project at the interface between Chemistry, Materials Science and Physics Dr. Renhao Dong aims to develop single- and few-layer magnetic (semi-)conductive C2DMOF films/nanosheets and accomplish electronic/magnetic structure engineering for functions in electronics and spintronics. As the key achievements, it is expected to establish novel electronic/magnetic structures and general synthesis strategies, delineation of reliable structure-transport relationships and superior device performance of C2DMOFs.
    Project: C2DMOF – Development of Functional Conjugated Two-Dimensional Metal-Organic Frameworks
    Partners: Faculty of Chemistry and Food Chemistry / Chair of Molecular Functional Materials (TU Dresden); Center for Advancing Electronics Dresden (cfaed)
    Expected start: 1.2.2020
    Information and contact details: https://tu-dresden.de/mn/chemie/mc/mc2/die-professur/gruppenleiter/dr-renhao-don...

    ERC Grants at TU Dresden
    The European Research Council (ERC) funds innovative projects by leading researchers at all career levels. There are currently 21 ongoing ERC Grants at TU Dresden. 7 of these are Starting Grants for early-career scientists. TUD researchers have received a total of 48 ERC Grants since 2008.

    Media inquiries
    TU Dresden Press Office
    Tel. +49 351 463-32398
    E-Mail: pressestelle@tu-dresden.de


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    Journalists, Scientists and scholars
    Chemistry, Materials sciences, Medicine, Physics / astronomy
    transregional, national
    Science policy
    English


     

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