Dr. Dr. Roland Schelker, head of the newly formed Translation Group “T-Cell Fitness” at the LIT and hematology/oncology medical specialist at the University Hospital Regensburg, receives a 75,000 USD G-Rex Grant by ScaleReady LLC. The grant will be used for advancing preclinical research projects focused on generating T stem cell memory (TSCM) cells.
TSCM cells are a special type of T cells that help the human immune system remember past infections or diseases and quickly turn into active fighter cells when the body needs them. Several preclinical research projects at the LIT explore the potential of these cells in therapies to treat various diseases, utilizing them due to their proven superior antitumor efficacy in preclinical models and their ability to persist long-term in vivo.
The scientists plan to use a G-Rex bioreactor. This bioreactor is a special device used to grow cells in the lab. Its unique design helps to produce large amounts of cells for research or medical purposes. The TSCM cells grown and expanded in the bioreactor will be used in multiple LIT research projects.
The grant has a duration of 18 months. During this time, the group led by Dr. Dr. Roland Schelker will generate preclinical data to improve and simplify existing manufacturing processes of TSCM cells. Pedro Noronha, Research Technician in the LIT Division of Functional Immune Cell Modulation, was intensively involved in the grant application process.
Dr. Dr. Roland C. Schelker
Head of Translation Group "T-Cell Fitness" at LIT,
Hematology/Oncology medical specialist at UKR
LIT- Leibniz Institute for Immunotherapy
c/o Universitätsklinikum Regensburg
Franz-Josef-Strauß-Allee 11
93053 Regensburg
Phone: +49 941 944 18374
Email: roland.schelker@ukr.de
Dr. Dr. Roland Schelker (left) and Pedro Noronha (right) with bioreactor
Vincent Schmucker
UKR Fotoabteilung
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