Graphic of a renal cell with water channels (aquaporin-2, AQP2) in the cell (left image) and with aquaporin-2 in the plasma membrane (right image, above). For example, when a person is thirsty, the hormone AVP triggers a signaling cascade and thereby elicits the redistribution of the water channels from the cell interior to the plasma membrane. The cell then directs water from primary urine via other water channels (AQP3 and 4, Fig. on the right, the right side of the cell) into the bloodstream and tissues.
(Graphic: Enno Klußmann/ Copyright: MDC)
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