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Image for: Blockade der DNA-Reparatur treibt Krebszelle in den Tod - Präklinische Studie zu Pankreastumoren


Im Mausmodell sprechen jene Tumoren mit zusätzlichem ATM Verlust (AKC) signifikant besser auf die Therapiekombination mit PARP, ATR und DNA-PK Inhibition (PAD) an, als die allgemein verwendeten Kontrollen mit einfacher KRAS Mutation (KC).
Im Mausmodell sprechen jene Tumoren mit zusätzlichem ATM Verlust (AKC) signifikant besser auf die Therapiekombination mit PARP, ATR und DNA-PK Inhibition (PAD) an, als die allgemein verwendeten Kontrollen mit einfacher KRAS Mutation (KC).

Klinik für Innere Medizin 1

Uniklinikum Ulm

(1445 KB, 3543 x 4158 pixels)

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