A: Überblick über die Bindung des Kasugamycins (Ksg, rot) an die kleine 30S-Untereinheit des Ribosoms (grau) von T. thermophilus. Die mRNA ist grün dargestellt, die Initiator-tRNA orange. B: Detaildarstellung der Überlappung des Kasugamycins mit der mRNA an der Bindungsstelle des Ribosoms. Die nicht korrekt ans Ribosom gebundene mRNA kann nicht mehr mit der tRNA wechselwirken. Dadurch wird auch die Bindung der tRNA an die 30S-Untereinheit des Ribosoms verhindert.
Abbildung: MPI für molekulare Genetik
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