Abbildung: Schematische Zeichnung einer Mikrostruktur, typische Originalmaße: 9 mm Länge, 3 mm Breite, 50 µm Kanalbreite. Die Knochenmarkzellen (hier: mesenchymale Stromazellen, kurz: MSC) und die Stammzellen (HSC) bzw. Leukämiestammzellen (LSC) können vor dem Experiment in separaten Reservoiren ansgesiedelt werden. Nach Bildung der Botenstoffe durch die MSC und Ausbildung des chemischen Gradienten beginnen die Stammzellen durch den Kanal in Richtung des MSC-Reservoirs zu wandern.
Quele: AG Prof. A. Ho
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