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Links: TBK1 induziert den Abbau seiner verwandten Kinase IKKepsilon. Rechts: Bei pathogen-induziertem Abbau oder genetischem Verlust von TBK1 ist die IKKepsilon-Proteinstabilität nicht mehr reduziert und somit der IKKepsilon-Proteinspiegel stark erhöht.
Abbildung: Frontiers in Immunology/DOI: 10.3389/fimmu.2023.1073608
(852 KB, 2538 x 2254 pixels)
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