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Nachrichten, Termine, Experten
Nachrichten, Termine, Experten
PROTACs and E3 ligases: PROTACs link a target protein (protein of interest, POI) with an E3 ligase, which mediates the ubiquitin labeling (yellow) of the POI via an E2 enzyme. The POI is then degraded in the proteasome shredder (blue).
Source: Institute of Biochemistry II
Copyright: Goethe University Frankfurt
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