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14.09.2015 17:00

Nanotechnology with proteins

Thomas Richter Öffentlichkeitsarbeit
Georg-August-Universität Göttingen

    For over two decades, scientists have been using DNA to design nanomaterials. Researchers from the University of Göttingen and the Medical School Hanover, both in Germany, have now discovered a new method to use proteins to construct two-dimensional webbings. The results were published in the scientific journal Nature Nanotechnology.

    Press release No. 207/2015

    Nanotechnology with proteins
    Göttingen scientists test new method of constructing two-dimensional structures

    (pug) For over two decades, scientists have been using DNA to design nanomaterials. Researchers from the University of Göttingen and the Medical School Hanover, both in Germany, have now discovered a new method to use proteins to construct two-dimensional webbings. The results were published in the scientific journal Nature Nanotechnology.

    The use of proteins in nanotechnology is a largely unexplored area. "However, due to their complex structure, proteins offer many possibilities to develop novel materials with unique properties," explains Dr. Iwan A.T. Schaap from Göttingen University’ Third Institute of Physics. The protein clathrin is normally involved in the formation of transport vesicles inside cells. The scientists show in their study that clathrin can also be used to form two-dimensional webbings on almost any type of surface. "This could revolutionize the design of biological sensors and biosynthetic reactors," says Dr. Schaap.

    After the researchers composed the clathrin-building blocks into a regular hexagonal lattice with a periodicity of only 30 nanometers, they developed a stabilization scheme. "It is essential that the protein structures are robust so that the nanotechnological devices will have a long lifetime and shelf-life," explains Dr. Schaap. Finally, the researchers showed how the clathrin webbings can be converted into functional devices by the binding of small metallic particles and active biomolecules. The researchers will continue their work on these novel protein structures with the aim of developing more efficient nanotechnological devices that can be used for sensing applications and the synthesis of biomolecules.

    Original publication: Philip N. Dannhauser et al. Durable protein lattices of clathrin that can be functionalized with nanoparticles and active biomolecules. Nature Nanotechnology 2015. Doi: 10.1038/nnano.2015.206.

    Contact:
    Dr. Iwan A.T. Schaap
    Georg-August-Universität Göttingen
    Faculty of Physics – III. Physical Institute
    Friedrich-Hund-Platz 1, 37077 Göttingen, Germany
    Phone +49 551 39-22816
    Email: ischaap@gwdg.de


    Weitere Informationen:

    http://www.iwanschaap.com


    Bilder

    Electron micrograph of a rough aluminium surface coated with a regular clathrin webbing (size is approximately 1.5 x 1.5 micrometers).
    Electron micrograph of a rough aluminium surface coated with a regular clathrin webbing (size is app ...
    Foto: Universität Göttingen
    None


    Merkmale dieser Pressemitteilung:
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    Biologie, Chemie, Medizin, Physik / Astronomie, Werkstoffwissenschaften
    überregional
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    Englisch


     

    Electron micrograph of a rough aluminium surface coated with a regular clathrin webbing (size is approximately 1.5 x 1.5 micrometers).


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