idw – Informationsdienst Wissenschaft

Nachrichten, Termine, Experten

Grafik: idw-Logo
Grafik: idw-Logo

idw - Informationsdienst

Thema Corona

Science Video Project

idw-News App:


Google Play Store

08.10.2021 16:06

On our way to the production of artificial heart tissue: Bayreuth research at Deutsches Museum Nuremberg

Christian Wißler Pressestelle
Universität Bayreuth

    At the recently opened Deutsches Museum Nuremberg, the University of Bayreuth offers insights into its expertise in the field of biofabrication involving unique materials, for example spider silk. Research led by Prof. Dr. Thomas Scheibel at the Biomaterials research group combines natural growth processes and technical systems with the aim of specifically rebuilding damaged tissue in organs, skin, nerves, and tendons. Consequently, in the "Body & Mind" exhibition area, one of the exhibits is a bioreactor from the Department of Biomaterials that simulates the cultivation of heart muscle tissue.

    For the regeneration of natural tissue, the Bayreuth researchers use bio-inks with which tissue-like structures can be 3D printed. These consist of two components: a scaffold unique in the world made of biotechnologically produced spider silk proteins and encapsulated living cells. These are able to proliferate along the scaffold structures so that new functional tissue gradually emerges.

    In cooperation with a research team at FAU Erlangen-Nuremberg led by Prof. Dr Felix Engel, the Bayreuth scientists are currently working on the possibility of producing functional heart tissue using 3D bioprinting. A 3D printer that produces the necessary scaffold structures is therefore also among the exhibits. The artificial tissue produced will one day be used in clinical medicine, among other things, to compensate for example for the loss of heart muscle cells due to disease. Using the same principle, it will then also be possible to produce artificial tissue from tendons, nerves, and skin. Accompanying microscope images of muscle cells and short film sequences showing contracting muscle cells on the scaffold structures make it clear to museum visitors that clinical applications of this research work could soon be within reach. "The new Deutsches Museum Nuremberg sees itself as a museum of the future that shows the public particularly innovative technologies reaching far into the future. It is therefore an ideal place to draw attention to the enormous potential of biofabrication," says Scheibel.

    The University of Bayreuth is the first and only provider to have brought the topic of "biofabrication" to the international university platform edX. The MOOC (Massive Open Online Course) "Biomaterials and Biofabrication: Design, Engineering & Innovation" is aimed at people specifically interested in materials research in the medical field, but also at people with no prior knowledge who wish to expand their knowledge of biomaterials, biomedical engineering, additive manufacturing, and tissue engineering, and to gain insights into the future of biofabrication.

    Biofabrication research at the University of Bayreuth is interdisciplinary: Biotechnology, engineering sciences, material sciences, polymer chemistry, and cell biology are all involved. The Keylab "Adaptive Biomanufacturing" of the Bavarian Polymer Institute (BPI) supports this work with state-of-the-art 3D processing as well as analytical microscopy technology. The Universities of Bayreuth, Erlangen-Nuremberg, and Würzburg have joined forces in the Transregio Collaborative Research Centre TRR225 "From the fundamentals of biofabrication to functional tissue models" to form a powerful network. The research work on heart muscle tissue exhibited in the museum is one of the fruits of this cooperation.

    Wissenschaftliche Ansprechpartner:

    Prof. Dr. Thomas Scheibel
    Chair of Biomaterials
    Faculty of Engineering Science (ING.) of the University of Bayreuth
    University of Bayreuth
    Prof.-Rüdiger-Bormann-Str. 1
    Phone: +49 (0)921 / 55-6701


    The biofabrication exhibit at the Deutsches Museum Nürnberg, consisting of a bioreactor (left), a microscopy station with samples of heart muscle tissue (centre), and a 3D printer (right).
    The biofabrication exhibit at the Deutsches Museum Nürnberg, consisting of a bioreactor (left), a mi ...

    © Deutsches Museum Nürnberg.

    The bioreactor simulating the cultivation of heart muscle tissue.
    The bioreactor simulating the cultivation of heart muscle tissue.

    © Deutsches Museum Nürnberg.

    Merkmale dieser Pressemitteilung:
    Journalisten, Lehrer/Schüler, Studierende, Wissenschaftler, jedermann
    Biologie, Chemie, Medizin, Werkstoffwissenschaften
    Buntes aus der Wissenschaft, Forschungs- / Wissenstransfer



    Die Suche / Erweiterte Suche im idw-Archiv

    Sie können Suchbegriffe mit und, oder und / oder nicht verknüpfen, z. B. Philo nicht logie.


    Verknüpfungen können Sie mit Klammern voneinander trennen, z. B. (Philo nicht logie) oder (Psycho und logie).


    Zusammenhängende Worte werden als Wortgruppe gesucht, wenn Sie sie in Anführungsstriche setzen, z. B. „Bundesrepublik Deutschland“.


    Die Erweiterte Suche können Sie auch nutzen, ohne Suchbegriffe einzugeben. Sie orientiert sich dann an den Kriterien, die Sie ausgewählt haben (z. B. nach dem Land oder dem Sachgebiet).

    Haben Sie in einer Kategorie kein Kriterium ausgewählt, wird die gesamte Kategorie durchsucht (z.B. alle Sachgebiete oder alle Länder).