idw – Informationsdienst Wissenschaft

Nachrichten, Termine, Experten

Grafik: idw-Logo
Grafik: idw-Logo

idw - Informationsdienst
Wissenschaft

Science Video Project
idw-Abo

idw-News App:

AppStore

Google Play Store



Instanz:
Teilen: 
23.08.2024 08:51

Artificial intelligence improves lung cancer diagnosis

Mathias Martin Kommunikation und Marketing
Universität zu Köln

    New AI-based digital platform enables extremely fast and accurate analysis of tissue sections from lung cancer patients / publication in ‘Cell Reports Medicine’

    A team of researchers from the University of Cologne’s Faculty of Medicine and University Hospital Cologne, led by Dr Yuri Tolkach and Professor Dr Reinhard Büttner, has created a digital pathology platform based on artificial intelligence. The platform uses new algorithms developed by the team and enables fully automated analysis of tissue sections from lung cancer patients. The platform makes it possible to analyse digitized tissue samples on the computer for lung tumours more quickly and accurately than before. The study ‘Next generation lung cancer pathology: development and validation of diagnostic and prognostic algorithms’ has been published in the journal Cell Reports Medicine.

    Lung cancer is one of the most common tumours/cancers in humans and has a very high mortality rate. Today, the choice of treatment for patients with lung cancer is determined by pathological examination. Pathologists can also identify molecularly specific genetic changes that allow for personalized therapy. Over the past few years, pathology has undergone a digital transformation. As a result, microscopes are no longer needed. Typical tissue sections are digitized and then analysed on a computer screen. Digitalization is crucial for the application of advanced analytical methods based on artificial intelligence. By using artificial intelligence, additional information about the cancer can be extracted from pathological tissue sections – something that would not be possible without AI technology.

    “We also show how the platform could be used to develop new clinical tools. The new tools can not only improve the quality of diagnosis, but also provide new types of information about the patient’s disease, such as how the patient is responding to treatment,” explained physician Dr Yuri Tolkach from the Institute of General Pathology and Pathological Anatomy at University Hospital Cologne, who led the study.

    In order to prove the broad applicability of the platform, the research team will conduct a validation study together with five pathological institutes in Germany, Austria and Japan.

    Press and Communications Team:
    Mathias Martin
    +49 221 470 1705
    m.martin@verw.uni-koeln.de

    Press Spokesperson: Dr Elisabeth Hoffmann – e.hoffmann@verw.uni-koeln.de


    Wissenschaftliche Ansprechpartner:

    Dr Yuri Tolkach
    Institute of General Pathology and Pathological Anatomy, University Hospital Cologne
    +49 221 478 87023
    iurii.tolkach@uk-koeln.de


    Originalpublikation:

    Next generation lung cancer pathology: development and validation of diagnostic and prognostic algorithms’, Cell Reports Medicine,
    DOI: 10.1016/j.xcrm.2024.101697


    Bilder

    The image shows how the algorithm initially processes the typically stained tissue section (left) and creates a map in which different tissue types can be seen in different colors (blue is the tumor, in this case an adenocarcinoma of the lung)
    The image shows how the algorithm initially processes the typically stained tissue section (left) an ...
    Dr. Yuri Tolkach
    Dr. Yuri Tolkach


    Merkmale dieser Pressemitteilung:
    Journalisten, Studierende, Wissenschaftler, jedermann
    Biologie, Ernährung / Gesundheit / Pflege, Informationstechnik, Medizin
    überregional
    Forschungsergebnisse, Wissenschaftliche Publikationen
    Englisch


     

    Hilfe

    Die Suche / Erweiterte Suche im idw-Archiv
    Verknüpfungen

    Sie können Suchbegriffe mit und, oder und / oder nicht verknüpfen, z. B. Philo nicht logie.

    Klammern

    Verknüpfungen können Sie mit Klammern voneinander trennen, z. B. (Philo nicht logie) oder (Psycho und logie).

    Wortgruppen

    Zusammenhängende Worte werden als Wortgruppe gesucht, wenn Sie sie in Anführungsstriche setzen, z. B. „Bundesrepublik Deutschland“.

    Auswahlkriterien

    Die Erweiterte Suche können Sie auch nutzen, ohne Suchbegriffe einzugeben. Sie orientiert sich dann an den Kriterien, die Sie ausgewählt haben (z. B. nach dem Land oder dem Sachgebiet).

    Haben Sie in einer Kategorie kein Kriterium ausgewählt, wird die gesamte Kategorie durchsucht (z.B. alle Sachgebiete oder alle Länder).